Lactoferrin with Royal Jelly is prepared with goat milk and royal jelly that supplies nutrients, growth factors for support of immune system in children.
Lactoferrin is a peptide glycoprotein that belongs to the transferrin family, plays a role in binding and transporting iron in the body, as well as immuno modulatory and antioxidant activities, it is a natural anti-viral, anti-bacterial and anti-inflammatory that supports the immune system and gut microflora, promote healthy sleep (1-9).
Lactoferrin is a protein naturally found in breastmilk (cow milk and human milk), and is also found in fluids in the eye, nose, respiratory tract, intestine, and elsewhere.
The antiviral properties of lactoferrin make it a great natural supplement that could also be used as an adjunct for COVID-19 and for various other Respiratory Tract Infections (RTIs) according to a team of researchers led by the University of Huddersfield (10).
It was found that Lactoferrin intake may improve sleep condition, especially morning symptoms in children above one year of age. (11-12)
Royal Jelly is a mix of yellow-white secretion produced by the worker honey bees to supply a principal food for queen honeybee. It is rich in minerals (mainly calcium and iron), vitamins (riboflavin, niacin, thiamine and B6, vit E), carbohydrates, and proteins fatty acids, sugars, biotin, sulfur, phosphorus, proteins, and essential amino acids.
Royal jelly for children is a great activator of the immune system since it helps fight infections and has revitalizing properties, increasing the body’s resistance.
Compounds of Royal Jelly like jelleins, royalisin, MRJPs, royalactin, and apisimin could be classified as antimicrobial peptides, appear to be a natural alternative to conventional antibiotics (13)
Support Gut Health
Antiviral activity
Antimicrobial activity
Supports Immune System
Anti-inflammatory
Supports Iron Absorption
Take 1 capsule daily, preferably in the morning, with or without food.
Immune Stress or Mucosal Inflammation:
Use 2 capsules daily, divided between morning and early afternoon. For gut-eye-immune axis support, take consistently for 2–3 months.
Note:
Contains royal jelly and bovine-derived lactoferrin — avoid in known allergy cases.
Other ingredients: Crystalline cellulose, Flavour (yogurt essence), Calcium stearate, Silicon dioxide
Follow the recommended daily intake.
Check the ingredient list and avoid consumption if you have food allergies.
Keep out of reach of children.
Consume immediately after opening.
Discontinue use if you experience discomfort or if it does not suit your body.
Color variations may occur, but this does not affect quality.
Not suitable for children under 18, pregnant or breastfeeding women, or individuals with nervous irritability, insomnia, or hypertension.
This product is not a medicine.
Contra-indications:
Do not take “Lactoferrin with Royal Jelly” if you are Hypersensitive (allergic) to to any of the ingredients: Lactoferrin, Royal Jelly, Goat Milk.
Consult your Healthcare Practitioner first and take Special Precautions prior to use of “Lactoferrin with Royal Jelly” if Pregnant of breasfeeding.
Oda H, Wakabayashi H, Tanaka M, Yamauchi K, Sugita C, Yoshida H, Abe F, Sonoda T, Kurokawa M. Effects of lactoferrin on infectious diseases in Japanese summer: A randomized, double-blinded, placebo-controlled trial. J Microbiol Immunol Infect. 2021 Aug;54(4):566-574.
Hu Y, Meng X, Zhang F, Xiang Y, Wang J. The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor. Emerg Microbes Infect. 2021 Dec;10(1):317-330
Wakabayashi H, Oda H, Yamauchi K, Abe F. Lactoferrin for prevention of common viral infections. J Infect Chemother. 2014 Nov;20(11):666-71.
Vitetta L, Coulson S, Beck SL, Gramotnev H, Du S, Lewis S. The clinical efficacy of a bovine lactoferrin/whey protein Ig-rich fraction (Lf/IgF) for the common cold: a double blind randomized study. Complement Ther Med. 2013 Jun;21(3):164-71.
Kevin K. Darmawan, Tom C. Karagiannis, Jeff G. Hughes, Darryl M. Small, Andrew Hung. (2022) Molecular modeling of lactoferrin for food and nutraceutical applications: insights from in silico techniques. Critical Reviews in Food Science and Nutrition 0:0, pages 1-24.
Yamauchi K, Wakabayashi H, Hashimoto S, Teraguchi S, Hayasawa H, Tomita M. Effects of orally administered bovine lactoferrin on the immune system of healthy volunteers. Adv Exp Med Biol. 1998;443:261-5.
Mohamed WA, Salama RM, Schaalan MF. A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway. Biomed Pharmacother. 2019 Mar;111:714-723.
Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Frum T, Kadambi NS, Amin AT, O'Meara TR, Pretto CD, Spence JR, Huang J, Alysandratos KD, Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O'Meara MJ, Sexton JZ. Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19. bioRxiv [Preprint]. 2020 Dec 7:2020.05.27.117184.
Wotring, Jesse W. et al.Evaluating the in vitro efficacy of bovine lactoferrin products against SARS-CoV-2 variants of concern Journal of Dairy Science, Volume 105, Issue 4, 2791 – 2802
Akbar Shoukat Ali, Syed Shahzad Hasan, Chia Siang Kow, Hamid A. Merchant, Lactoferrin reduces the risk of respiratory tract infections: A meta-analysis of randomized controlled trials, Clinical Nutrition ESPEN, Vol 45, 2021,Pp 26-32.
Uesaki, S. & Imanaka, Hiromichi & Suido, Hirohisa & Suwa, M. & Matsumoto, M. & Kondo, S.. (2018). Effects of lactoferrin supplementation on sleep quality, mood states, and enteric environment in poor sleepers-Randomized, placebo-controlled, double-blind study-. Japanese Pharmacology and Therapeutics. 46. 55-63
Miyakawa M, Kubo S, Oda H, Motoki N, Mizuki M, Tsukahara T, Tanaka M, Yamauchi K, Abe F, Nomiyama T. Effects of Lactoferrin on Sleep Conditions in Children Aged 12-32 Months: A Preliminary, Randomized, Double-Blind, Placebo-Controlled Trial. Nat Sci Sleep. 2020 Sep 29;12:671-677.
Collazo N, Carpena M, Nuñez-Estevez B, Otero P, Simal-Gandara J, Prieto MA. Health Promoting Properties of Bee Royal Jelly: Food of the Queens. Nutrients. 2021 Feb 7;13(2):543.
