Nattokinase
7850
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Nattokinase is a kind of alkaline serine prostease with strong fibrinolytic and thrombolytic activity, which is secreted by Bacillus natto and discovered by Sumi et al(1). As endogenous fibrinolytic enzyme, nattokinase is functionally similar to husman plasmin
OVERVIEW
Nattokinase was reported to lower blood pressure by inhibiting the secretion of angiotensin-converting enzyme I and angiotensin II, and interact with fibrinogen in plasma to reduce blood viscosity, thereby lowering blood pressure (2).
Studies showed that nattokinase attenuates neovascularization in the retinas of mice with oxygen retinopathy (5), thus it can be useful in the treat ment of such diseases as retinopathy of prematurity, diabetic retinopathy, and retinal vein occlusion. Additionally it can be used as a as a vitreous cleavage supplement in the treatment of proliferative vitreoretinal diseases. According to recent studies Nattokinase has various pharmacological effects, such as improving microcirculation and lowering blood pressure (2), anticoagulation (3), preventing atherosclerosis (4), relieving retinal angiogenesis (5), anticancer (6), inhibiting inflammation and oxidative stress (7). In addition to the research of nattokinase in the fields of throm bosis and hypertension treatment, nattokinase can also be used as a drug or adjuvant to treat diseases such Alzheimer’s disease (AD) (8), retinopathy (5) hyperlipidemia (9) and oral mucositis (10).
FEATURES
DIRECTION OF USE
Take 1-2 capsules once or twice daily, on an empty stomach (at least 1 hour before or 2 hours after a meal) for optimal enzymatic activity.
Note:
Do not use with anticoagulant or antiplatelet medications unless under supervision. Discontinue 5–7 days before surgery.
OVERVIEW
Nattokinase was reported to lower blood pressure by inhibiting the secretion of angiotensin-converting enzyme I and angiotensin II, and interact with fibrinogen in plasma to reduce blood viscosity, thereby lowering blood pressure (2).
Studies showed that nattokinase attenuates neovascularization in the retinas of mice with oxygen retinopathy (5), thus it can be useful in the treat ment of such diseases as retinopathy of prematurity, diabetic retinopathy, and retinal vein occlusion. Additionally it can be used as a as a vitreous cleavage supplement in the treatment of proliferative vitreoretinal diseases. According to recent studies Nattokinase has various pharmacological effects, such as improving microcirculation and lowering blood pressure (2), anticoagulation (3), preventing atherosclerosis (4), relieving retinal angiogenesis (5), anticancer (6), inhibiting inflammation and oxidative stress (7). In addition to the research of nattokinase in the fields of throm bosis and hypertension treatment, nattokinase can also be used as a drug or adjuvant to treat diseases such Alzheimer’s disease (AD) (8), retinopathy (5) hyperlipidemia (9) and oral mucositis (10).
FEATURES
- Provides nutritional support for the maintenance and enhancement of normal healthy endogenous fibrinolysis
- Provides nutritional support for the inhibition of inflammation and oxidative stress
- Non-GMO material, non-irradiated, safe for daily use
DIRECTION OF USE
Take 1-2 capsules once or twice daily, on an empty stomach (at least 1 hour before or 2 hours after a meal) for optimal enzymatic activity.
Note:
Do not use with anticoagulant or antiplatelet medications unless under supervision. Discontinue 5–7 days before surgery.
Reviews
Since ive used two collagens and am very satisfied with them, left reviews on those products you can go and look, i am using nattokinase and i dont know if its a placebo or not, but i am not even finished with the bottle (been taking 2 pills per day), my feet are not as cold as always, i think it somehow managed to influence my blood flow down on my limbs. I need more testing more input but for now this product is promising for me as a guy who is into lots of sport activities, natural bodybuilding especially.